Potential CISC 499 projects
Project 1: MEG brain
imaging-based functional neural connectivity analysis
Magneto-Encephalography (MEG) data will be analyzed using the
free Matlab toolboxes to identify functional connectivity
strengths between different brain areas involved in reach
planning. So far we have obtained areas of interest and would
like to know how they connect to one another across different
frequency bands. To investigate that, we will use an
event-related causal modelling approach called orthogonalized
partial directed coherence.This will give us a
frequency-dependent connectivity between multiple areas for
each point in time in the reaching task at hand. One challenge
will be to graphically represent these high-dimensional data.
Project 2: DTI anatomical brain connectivity analysis
Diffusion Tensor Imaging (DTI) data will be analyzed using
free Matlab software (such as fanDTasia) in order to uncover
the anatomical white matter tract connectivity between brain
areas involved in reach planning. We will place seeds in a
series of 16 bi-lateral brain regions to look for likely
anatomical connections between all 32 regions of interest in
the brain. We will then develop graphical tools to reduce
dimensionality and visualize only relevant connections.
For more details please contact me.